Ph.D. in Plastic Surgery and Regenerative Medicine
Shanghai Ninth People's Hospital, SJTU · Department of Plastic and Reconstructive Surgery
Dr. Xinyi Dai
XINYI DAI · M.D. / Ph.D.
Specialist in Scar Repair and Functional Reconstruction
American Association of Plastic Surgeons
Shanghai Science and Technology Commission
Tissue Engineering and Regenerative Medicine International Society
About
About Me

Associate Chief Physician
Associate Chief Physician · Dept. of Plastic & Reconstructive Surgery · Shanghai Ninth People's Hospital
Dr. Xinyi Dai serves as an Associate Chief Physician in the Department of Plastic and Reconstructive Surgery at Shanghai Ninth People's Hospital, affiliated with Shanghai Jiao Tong University School of Medicine. He holds a doctorate and postdoctoral experience from Germany and is a Constable Fellow of the American Association of Plastic Surgeons (AAPS), a member of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), and a recipient of Shanghai's 'Pujiang Talent' award.
From 2012 to 2016, Dr. Dai was awarded a national scholarship by the China Scholarship Council to pursue his doctoral studies at the Technical University of Munich (TUM), Germany. He graduated with the highest distinction, 'Summa Cum Laude', earning a Ph.D. in Plastic Surgery and Regenerative Medicine.
In 2014, Dr. Dai was selected through an international competitive process for the AAPS John D. Constable International Travelling Fellowship. He was invited to conduct academic visits at Harvard Medical School's Massachusetts General Hospital, NYU Langone Medical Center, and Johns Hopkins Hospital in the field of plastic and reconstructive surgery.
From 2016 to 2017, Dr. Dai undertook postdoctoral research at the University Medical Center Göttingen, Germany, focusing on the mechanisms and translational applications of scarless wound healing. His representative work was published in NPG Asia Materials, part of the Nature Publishing Group, and was highlighted in Science Translational Medicine.
Dr. Dai contributed to the Science special issue '125 Questions: Exploration and Discovery'. He is the chief editor of a 100,000-word popular science book titled 'The Missing Puzzle: The Fascinating World of Tissue Defect Repair and Regeneration', published by Shanghai Jiao Tong University Press.
Ph.D — Summa Cum Laude
Technical University of Munich, specialization in Plastic Surgery and Regenerative Medicine, graduated with highest honors
AAPS Constable Fellow
Selected through international competition for academic visits to Harvard MGH, NYU Langone, and Johns Hopkins
Nature Portfolio Publication
Research findings published in NPG Asia Materials, highlighted in Science Translational Medicine
Shanghai 'Pujiang Talent' Class A
Principal Investigator on a National Natural Science Foundation of China General Program and a Shanghai Pujiang Talent Plan project
Clinical Expertise
Expertise
Specializing in the reconstruction of tissue defects caused by trauma, tumors, and diseases, with extensive expertise in both clinical practice and foundational research
Repair and Reconstruction of Tissue/Organ Defects
Tissue & Organ Defect Reconstruction
Microsurgical reconstruction and replantation of tissue defects resulting from trauma, tumors, and diseases, with a focus on functional and aesthetic restoration of complex wounds.
Microsurgical Reconstruction
Microsurgical Reconstruction
Utilization of microsurgical techniques for tissue transplantation and vascular anastomosis, ensuring precise and high-quality reconstruction of composite tissue defects.
Functional and Aesthetic Scar Revision
Functional and Aesthetic Scar Revision
Functional and aesthetic correction of scar deformities and limb malformations, aimed at restoring normal appearance and function for patients.
Oncoplastic Surgery
Oncoplastic Surgery
Surgical resection and reconstruction of benign and malignant cutaneous and soft tissue tumors, balancing radical excision with aesthetic considerations to minimize postoperative functional and cosmetic impact.
Medical Aesthetics
Medical Aesthetics
Lower eyelid rejuvenation, brow lift surgery, and aesthetic injections.
Tissue Engineering & Regenerative Medicine
Tissue Engineering & Regenerative Medicine
Mechanistic and translational research on scarless wound healing.
Patient Education
Scar Education Library
A clinical knowledge library on scar recognition, function, treatment planning, and reconstruction.
- Types & Mechanisms
Hypertrophic Scars vs. Keloids
After a wound has healed, redness, elevation, and hardening are medically often classified as pathological scarring, which mainly includes hypertrophic scars and keloids.
Read article - Treatment Planning
Can Scars Be Completely Removed?
From a medical point of view, a scar that has already formed is very difficult to restore completely to normal skin that looks as if it had never been injured.
Read article - Treatment Planning
How Doctors Develop a Scar Treatment Plan
There is no single scar treatment that suits everyone. Scars differ in their causes, location, thickness, color, firmness, mobility, symptoms, and risk of recurrence, and the treatment goals are also different.
Read article - Reconstructive Strategies
When Do Scars Need Reconstructive Surgery?
Scars are the result of wound healing. Mild scars may only appear darker, locally red, or slightly firm to the touch, and may have little effect on daily life.
Read article - Pediatric Scars
Pediatric Scar Management: Children Need Different Plans
Children are still growing and developing, and their skin, bones, joints, muscles, and psychological state are all changing dynamically.
Read article - Burn Scars
Long-Term Management and Reconstruction Strategies for Burn Scars
The skin repair process after a burn is often more complex than that of an ordinary incision, because burns may cause large areas of skin loss, dermal injury, destruction of skin appendages, and damage to blood vessels and nerves.
Read article
Education & Training
Education & Training
Shanghai Ninth People's Hospital, SJTU
Department of Plastic & Reconstructive Surgery · Associate Chief Physician
Principal investigator of a National Natural Science Foundation of China General Program, focusing on the molecular mechanisms and translational research of scarless wound healing.
University Medical Center Göttingen
Universitätsmedizin Göttingen, Germany
Postdoctoral training with representative work published in Nature Portfolio's NPG Asia Materials and highlighted by Science Translational Medicine.
AAPS John D. Constable Fellowship
American Association of Plastic Surgeons
Technical University of Munich
Technische Universität München (TUM), Germany
Awarded a national government-sponsored doctoral scholarship to study in Germany, majoring in Plastic Surgery and Regenerative Medicine. Passed the doctoral defense with the highest distinction, 'Summa Cum Laude', and received a Ph.D. degree.
Publications
Selected Publications
Representative Articles
Wei Nie, Eric J. Marrotte, Rongyuan Xie, Hans-Gunther Machens, Arndt F. Schilling, Yi Shen, Michael Seeds, Anthony Atala, Xinyi Dai
Towards scarless repair: MMP-2 responsive drug releasing nanofibrous mat restores homeostasis via fibroblasts' activation.
Composites Part B: Engineering. 2025; Vol. 291, 111972.
Xinyi Dai, Juan Liu, Huaiyuan Zheng, Johannes Wichmann, Ursula Hopfner, Stefanie Sudhop, Carina Prein, Yi Shen, Hans Machens, Arndt Schilling.
Nano-formulated curcumin accelerates acute wound healing through Dkk-1 mediated fibroblast mobilization and MCP-1 mediated anti-inflammation.
NPG Asia Materials. 2017; (9), e368. Science Translational Medicine Highlight
Eberlin KR, Del Frari B, Dai X, Austen WG Jr.
The John D. Constable International Traveling Fellowship: A Reciprocal Education in Plastic Surgery.
Journal of Craniofacial Surgery. 2015; Jun; 26(4):1050-2.

Scientific Monographs · Chief Editor
The Missing Puzzle
This book explains complex biomedical concepts in simple language, delving into the different types and causes of tissue defects, as well as various tissue repair methods.
Shanghai Jiao Tong University Press · 100,000 Chinese characters · ISBN: 978-7-313-30847-4International Exchange
International Exchange
International Academic Conferences
Tissue Engineering and Regenerative Medicine International Society (TERMIS) Americas Annual Meeting
San Diego, USA
4th Tissue Engineering and Regenerative Medicine International Congress
Boston, USA
19th German Surgical Research Congress
Würzburg, Germany
26th German-Chinese Medical Annual Meeting
Essen, Germany
Visited Institutions
Massachusetts General Hospital
Harvard Medical School
Boston, USANYU Langone Medical Center
New York University
New York, USAJohns Hopkins Hospital
Johns Hopkins University
Baltimore, USATechnical University of Munich
TUM School of Medicine
Munich, GermanyUniversity Medical Center Göttingen
University of Göttingen
Göttingen, GermanyContact
Contact Information
Specialist Outpatient Clinic
Shanghai Ninth People's Hospital South Campus 9F, New Outpatient Building, Quxi Road, Huangpu District, Shanghai
Shanghai Ninth People's Hospital North Campus Plastic and Aesthetic Surgery Outpatient Department, 1F, Building 7, No. 280 Mohe Road, Baoshan District, Shanghai
Outpatient Information
- Department
- Plastic and Reconstructive Surgery, Plastic and Aesthetic Surgery
- Title
- Associate Chief Physician
- Expertise
- Scar Treatment · Tissue Defect Repair · Microsurgery
Appointments can be booked via the official hospital App or website. Check the current hospital schedule.
Academic Collaboration
Dr. Xinyi Dai, MD/PhD in Plastic and Reconstructive Surgery Focused on scar surgery, reparative treatment for scars and deformities, fine aesthetic scar repair, fine scar repair under microscopy, tissue-defect repair and reconstruction, oncoplastic surgery for surface tumors, and reconstructive surgery for limb deformities Academic discussion and collaboration are welcome.
Hospital Website
Dr. Xinyi Dai's profile on the official website of Shanghai Ninth People's Hospital
Linkhttps://www.9hospital.com.cn/article/41/214248.htmlMedical note: This page introduces professional credentials, research interests, and clinic information only. It is not a substitute for in-person consultation, diagnosis, or treatment.




